May 15, 2024 - AWH

The Silent Revolution in Women's Healthcare: Why Aspira's Unwavering AUP Signals a Tsunami of Growth

Aspira Women's Health Inc. has been quietly building a revolution in women's healthcare. While their Q1 2024 earnings call might appear, at first glance, to be a routine update of steady growth and strategic execution, there's a subtle signal hidden within the data that suggests something far more profound is underway.

The key lies in Aspira's average unit price (AUP) for their OvaSuite of tests. It remained remarkably stable at $369 for the quarter, mirroring the AUP of Q1 2023. This might seem unremarkable until we consider the significant shift in product mix between the two quarters. In Q1 2023, Ova1Plus dominated the volume. However, Q1 2024 saw a near 80-20 split between Ova1Plus and the newer OvaWatch, a test designed for longitudinal monitoring of potential ovarian masses.

This is where the silent revolution becomes audible. Launching a new diagnostic test almost always results in initial price dilution as physicians adopt the technology and payers negotiate reimbursement. Yet, OvaWatch's AUP is not only holding strong, it's rapidly converging with the established Ova1Plus pricing _faster_ than anticipated. This defiance of conventional launch dynamics points to an extraordinary level of underlying demand and confidence in the test's clinical utility.

Consider this: The recently published data in _Frontiers in Medicine_, demonstrating OvaWatch's potential to improve physician accuracy in predicting malignancy by over 400%, is creating waves within the medical community. This is coupled with the validation of OvaWatch's reliability for monitoring ovarian cancer risk in _Gynecologic Oncology_. These high-impact publications, combined with the longitudinal monitoring feature, offer a compelling narrative for physicians and patients seeking alternatives to the often drastic and life-altering consequences of surgical intervention.

The market is responding. March was the strongest month for OvaWatch in Q1 2024, and this momentum surged into April, becoming the second-largest volume month in the company's history – all this despite having two open sales territories. Aspira's strategic commercial refresh, including the elimination of unprofitable territories, the recruitment of a more experienced sales team, and the creation of an inside sales function, is laying the groundwork for efficient, scalable growth. The 22% increase in volume per full-time sales representative to 364 in Q1 2024 compared to the previous year further underscores the power of these strategic changes.

OvaWatch Volume Growth (Q1 2023 vs. Q1 2024)

Source: Aspira Women's Health Q1 2024 Earnings Call Transcript [Link to Transcript]

The Hypothesis: An AUP Surge is Imminent

We hypothesize that Aspira's unwavering AUP is a leading indicator of a dramatic surge in OvaWatch adoption and revenue. The company's focus on securing new reimbursement wins, with the Anthem agreement covering Blue Cross of California as a prime example, will further fuel this growth. We anticipate a significant increase in AUP over the coming quarters, potentially reaching or even surpassing the Ova1Plus AUP within the next year.

Why This Matters: Aspira's Impact on Healthcare Economics

This potential revenue surge is not just a financial story, it's a healthcare revolution. OvaWatch's ability to empower physicians with accurate and reliable non-invasive monitoring of potential ovarian masses has the potential to dramatically reduce unnecessary surgeries.

Let's quantify this impact. Aspira estimates over 1.2 million women develop an adnexal mass annually. If OvaWatch were to achieve even a 25% penetration of this market, with an average of two tests per patient per year at the current $369 AUP, that translates to over $221 million in annual revenue. Moreover, reducing unnecessary surgeries by even a fraction of this population would result in billions of dollars in healthcare cost savings.

Aspira's silent revolution isn't just about better diagnostics, it's about changing the paradigm of women's healthcare by offering less invasive, more cost-effective solutions. The unwavering AUP signals a tsunami of growth that's poised to transform the market and improve the lives of millions of women.

"Potential Impact of OvaWatch"

Reduced Surgeries: By providing accurate, non-invasive monitoring, OvaWatch could drastically reduce the number of unnecessary surgeries for adnexal masses.

Healthcare Cost Savings: Reducing surgeries translates to significant cost savings for the healthcare system, potentially reaching billions of dollars annually.

Improved Patient Outcomes: Fewer surgeries mean less risk, faster recovery, and improved quality of life for women.

"Fun Fact:"

Ovarian cancer is often called the "silent killer" because it often presents with vague symptoms that are easy to dismiss. Early detection is crucial for improving survival rates. Aspira's tests are empowering physicians to identify and monitor ovarian cancer risk earlier, giving women a better chance at a positive outcome.