Answers go deeper than the script: questioning keeps surfacing new concrete detail behind a positive development · broad
The model's full reasoning — Q3 2023 call → NOWe need answer only YES or NO. Need evaluate both gates. Need use transcript. Gate 1: positive current development in business, Q&A produces more concrete operating detail than prepared remarks. Main positive development: ONC201 ACTION study enrollment progressing, sites open, conferences, ONC206 dose escalation, publication. Q&A probes ONC206 details, patient response, dose escalation, timing, biomarkers. Does management add new specifics? Let's examine. Prepared remarks: ONC201 ACTION study 113 sites, enrollment progressing, expect interim data 2025. ONC206 protocol amendments approved, twice daily dosing up to 3 consecutive days weekly, PNOC and NIH studies enrolling, expect complete first half 2024. Previously reported GBM response on once-weekly schedule starting dose level 2, response ongoing as dose level increased. No DLTs. Publication in Cancer Discovery. Q&A: First question about site initiation enrollment feedback in Western Europe and Canada, timing full enrollment. Mike: engagement strong, Canada slower regulatory, no guidance full enrollment, expect first interim OS first half 2025. This is somewhat repeat, not much new. Second question ONC206: patient response duration, dose levels. Mike: patient on study about 1.5 years, durable, dose escalated to dose level 4. Josh: dose escalated at least twice since initial 100mg, deepening response. This is new specific detail not in prepared remarks (duration, dose level, deepening). That's one exchange. Third question ONC206 dose escalation: 100mg dose level twice weekly? Mike: next dose levels evaluating similar exposures fractionated over 3 days, escalate up, about 4 times dose weekly if to dose level 11. This is new specifics about dosing schedule. Another exchange. Fourth question: tumor location broad? Mike: primary CNS tumors heterogeneous; Allen: excluding H3 K27, otherwise broad. Some new. Fifth question: expense trajectory. Not relevant. Sixth question: biomarkers for ONC206. Josh: leveraging molecular info, potency increase, alternative target engagement, opportunities outside H3 K27, preclinical activity, responder endorses hypothesis, testing actionable alterations. This is somewhat general but adds some. Seventh question: ONC206 Phase 1 completion timing both studies. Mike: expect around same time, planning, if change update. Allen: demand high, filling cohorts. Some new.
| Ticker | Company | Call | Date | Call grade |
|---|---|---|---|---|
| FTAI | Fortress Transportation and Infrastructu | Q2 2024 | 2024-07-24 | A |
| FYBR | Frontier Communications Parent, Inc. | Q1 2024 | 2024-05-03 | B |
| TOL | Toll Brothers, Inc. | Q1 2024 | 2024-02-21 | A |
| GDDY | GoDaddy Inc. | Q4 2023 | 2024-02-13 | A |
| ZWS | Zurn Elkay Water Solutions Corporation | Q4 2023 | 2024-02-07 | B |
| TMUS | T-Mobile US, Inc. | Q4 2023 | 2024-01-25 | B |
| VCEL | Vericel Corporation | Q3 2023 | 2023-11-08 | A |
| WEAV | Weave Communications, Inc. | Q3 2023 | 2023-11-01 | B+ |
| MAC | The Macerich Company | Q3 2023 | 2023-10-31 | D |
| CMG | Chipotle Mexican Grill, Inc. | Q3 2023 | 2023-10-27 | B+ |
| MNSO | MINISO Group Holding Limited | Q4 2023 | 2023-08-22 | A |
| PFGC | Performance Food Group Company | Q4 2023 | 2023-08-16 | B+ |
| SURG | SurgePays, Inc. | Q2 2023 | 2023-08-12 | D |
| EVLV | Evolv Technologies Holdings, Inc. | Q2 2023 | 2023-08-10 | B+ |
| TREX | Trex Company, Inc. | Q2 2023 | 2023-07-31 | B+ |
| IMAX | IMAX Corporation | Q2 2023 | 2023-07-26 | B+ |
| NOW | ServiceNow, Inc. | Q2 2023 | 2023-07-26 | A |
| UTHR | United Therapeutics Corporation | Q1 2023 | 2023-05-03 | B |
| BRX | Brixmor Property Group Inc. | Q1 2023 | 2023-05-02 | A |
| MGM | MGM Resorts International | Q1 2023 | 2023-05-01 | A |
| EDU | New Oriental Education & Technology Grou | Q3 2023 | 2023-04-19 | B |
| PAYX | Paychex, Inc. | Q3 2023 | 2023-03-29 | B |
| ADPT | Adaptive Biotechnologies Corporation | Q4 2022 | 2023-02-14 | C |
| CUTR | Cutera, Inc. | Q3 2022 | 2022-11-05 | C |
| INMD | InMode Ltd. | Q3 2022 | 2022-10-27 | A |
| SHW | The Sherwin-Williams Company | Q2 2022 | 2022-07-27 | D |
| BFIN | BankFinancial Corporation | Q1 2022 | 2022-05-06 | A |
| ABNB | Airbnb, Inc. | Q1 2022 | 2022-05-03 | A |
| FAT | FAT Brands Inc. | Q4 2021 | 2022-03-21 | F |
| APLE | Apple Hospitality REIT, Inc. | Q4 2021 | 2022-02-23 | A |
| DV | DoubleVerify Holdings, Inc. | Q3 2021 | 2021-11-11 | B |
| ENV | Envestnet, Inc. | Q3 2021 | 2021-11-08 | B+ |
| AMH | American Homes 4 Rent | Q3 2021 | 2021-11-05 | B+ |
| BIGC | BigCommerce Holdings, Inc. | Q3 2021 | 2021-11-04 | B+ |
| SPSC | SPS Commerce, Inc. | Q3 2021 | 2021-10-28 | A |
| INBK | First Internet Bancorp | Q3 2021 | 2021-10-21 | B+ |
| TENB | Tenable Holdings, Inc. | Q2 2021 | 2021-07-27 | A |
| SNY | Sanofi | Q3 2018 | 2018-10-31 | B+ |
| GAIA | Gaia, Inc. | Q2 2018 | 2018-08-06 | A |
| ORAN | Orange SA | Q2 2018 | 2018-07-26 | B |
| MKC | McCormick & Company, Incorporated | Q2 2018 | 2018-06-28 | C+ |
| FOSL | Fossil Group, Inc. | Q1 2018 | 2018-05-08 | C |
| VRTX | Vertex Pharmaceuticals Incorporated | Q1 2018 | 2018-04-26 | C+ |
| SNDR | Schneider National, Inc. | Q1 2018 | 2018-04-26 | A |
| ROKU | Roku, Inc. | Q4 2017 | 2018-02-21 | A |
| LIND | Lindblad Expeditions Holdings, Inc. | Q2 2017 | 2017-08-06 | C |
| CCOI | Cogent Communications Holdings, Inc. | Q2 2017 | 2017-08-03 | B |
| INTU | Intuit Inc. | Q3 2017 | 2017-05-23 | A |
| SAH | Sonic Automotive, Inc. | Q1 2017 | 2017-04-26 | C |
| FIVN | Five9, Inc. | Q4 2016 | 2017-02-17 | A |
| SQ | Square's | Q2 2016 | 2016-08-04 | A |
| SEM | Select Medical Holdings Corporation | Q1 2016 | 2016-05-06 | C+ |
| PLNT | Planet Fitness, Inc. | Q4 2015 | 2016-03-03 | A |
| BECN | Beacon Roofing Supply, Inc. | Q1 2016 | 2016-02-05 | B |
APLE · Q4 2021 → YESThe task is to evaluate two gates based on the earnings call transcript and return YES only if both are YES, otherwise NO. Answer with exactly YES or NO. YES The transcript shows a clear positive current development in the company's hotel portfolio recovery, particularly around Q1 2022 demand trends and operational metrics. In prepared remarks, Justin Knight and Liz Perkins highlight overall RevPAR improvement, leisure strength, and business travel recovery, but without granular February specifics.
MKC · Q2 2018 → YESThe task is to evaluate two gates based on the earnings call transcript and return YES only if both are YES, otherwise NO. YES NO (Gate 2 fails because the Frank’s/French’s growth is repeatedly tied to specific large retailers, national accounts, and one major customer whose shelf-reset decisions and promotional activity are named or implied as key drivers; the transcript never establishes a broad, granular base of many independent counterparties whose small decisions are widening adoption.
GAIA · Q2 2018 → YESThe task is to evaluate two gates based on the earnings call transcript and return YES only if both are YES, otherwise NO. Answer with exactly YES or NO. YES The transcript shows a positive current development in organic subscriber growth and the member referral program. Prepared remarks note organic contributions over 40% and reduced marketing spend. Q&A provides additive details: specific referral mechanics (7-day free watch), ambassador program vs.